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Health of Tomorrow

A Mountaineer Reaches for the ‘Everest’ of his Cancer Research Career

A Mountaineer Reaches for the ‘Everest’ of his Cancer Research Career

A Mountaineer Reaches for the ‘Everest’ of his...

New insights into the immune system are driving a recent resurgence in investigating vaccines that fight cancer tumors.  ...

How Immuno-Oncology Taps Into the Body’s Own Immune System to Fight Cancer

How Immuno-Oncology Taps Into the Body’s Own Immune System to Fight Cancer

How Immuno-Oncology Taps Into the Body’s Own...

One of the most important advances in cancer therapies is a field known as immuno-oncology, which uses methods that tap into a patient’s own immune system to detect and destroy cancer cells. Experts predict that immuno-oncology will become one of the pillars of cancer treatment, alongside more...

How Fragment-Based Drug Screening Is Like the ‘Tetris’ of Drug Design

How Fragment-Based Drug Screening Is Like the ‘Tetris’ of Drug Design

How Fragment-Based Drug Screening Is Like the ...

In recent years, an alternative approach to finding drug candidates has emerged, known as fragment-based drug design.  With the fragment-based approach, you’re starting with a smaller pool of much simpler compounds about half the size of HTS molecules — mere fragments. 

Cryo-Electron Microscope Opens Resolution Revolution for Biological Imaging

Cryo-Electron Microscope Opens Resolution Revolution for Biological Imaging

Cryo-Electron Microscope Opens Resolution...

The cryo-electron microscope, or cryo-EM, is allowing scientists to image structures as small as viruses and ribosomes — the part of the cell where proteins are synthesized. More importantly, it does this without the need to turn the samples into crystals — the often tricky step needed when using...

When Diversity Means Better Medicine

When Diversity Means Better Medicine

When Diversity Means Better Medicine

By tapping into more diverse genomes, researchers are gaining novel insights into disease and drug safety. 

Seeing Science in the Everyday: Glow Sticks That Detect Cancer

Seeing Science in the Everyday: Glow Sticks That Detect Cancer

Seeing Science in the Everyday: Glow Sticks...

The same science behind glow sticks and the crime scene chemical luminol – which glows blue in the presence of blood – is now being used to develop cutting-edge tools to detect cancer and other medical diagnoses.

A New Frontier for AI: Helping Scientists Develop Potential New Medicines

A New Frontier for AI: Helping Scientists Develop Potential New Medicines

A New Frontier for AI: Helping Scientists...

Austin Huang, Associate Director and the Biomedical Data Science lead in Pfizer’s Genome Sciences and Technologies group, explains the role of artificial intelligence in drug development.

The Great Migration: Tracking Immune Cells’ Travels

The Great Migration: Tracking Immune Cells’ Travels

The Great Migration: Tracking Immune Cells’...

Our immune cells, in particular, are always on the move, constantly patrolling the body for foreign invaders. For reasons that scientists don’t fully understand, the immune system sometimes becomes confused, sending a fleet of fighters to attack the body’s own tissues and organs. The result...

Fixing Broken Body Clocks

Fixing Broken Body Clocks

Fixing Broken Body Clocks

Every living being from fungi to frogs has an internal clock that normally runs on a 24-hour cycle.  In humans, this master clock resides in a tiny region of the brain’s hypothalamus and controls everything from hunger and sleep patterns to daily hormone fluctuations and body temperature.In...

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