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Main navigation

  • Foundations of Science

    • Understanding Conditions
      • Autoimmune Diseases
      • Cancer
      • Cardiovascular & Metabolism
      • Rare Diseases
      • Infectious Diseases

    • Biology Basics
      • Genetics
      • Immune System

    • Science in the Everyday
  • Advancing Medical Research

    • Innovations
      • Drug Discovery
      • Clinical Trials
      • Our Scientists
      • Technology

    • Focus Areas
      • Covid-19
      • Immunology
      • Oncology
      • Vaccines
      • Cardiovascular & Metabolism
  • podcasts
Foundations of Science

Protease Inhibitors to Fight COVID-19: Stopping the Virus’s Life Cycle

Protease Inhibitors to Fight COVID-19: Stopping the Virus’s Life Cycle

Protease Inhibitors to Fight COVID-19: Stopping the Virus’s Life Cycle

All viruses, including SARS-CoV-2, the virus that causes COVID-19, have the same goal: invade our cells, use our cells’ internal machinery to make copies of itself, and then release the newly made virus to infect more of our cells. But protease inhibitors, a class of drugs long used to treat HIV and hepatitis C, have been shown to stop this process — known as the viral life cycle. These drugs work by blocking a critical enzyme, a protease, that the virus needs to replicate. Read on to learn more.

 

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